Technology

BioOptico develops unique augmented reality tools for endoscopy and other video applications in medicine. A brief overview of two of our most central augmentation principles follows.

Spectral enhancement
Spectral information (color) is gathered frame by frame and pixel by pixel. By calibrating or learning the algorithm, various tissue conditions can be recognized, objectively mapped and/or visually enhanced. The output is shown as a color coded overlay in the real-time video. Typical applications include recognizing blood perfusion of tissues, quantifying the composition of mixed tissues and deriving the thickness of a tissue layer on top of another.

Texture enhancement
Texture information (derived as local intensity variation) is gathered frame by frame and pixel by pixel. Similar to spectral enhancement, the surface or the bulk structure of tissues in various situations is recognized, mapped, enhanced and visually presented. Typical applications include recognizing rough surfaces caused by cellular degeneration, quantifying turbidity of body fluids and deriving fibrillated degeneration states of tissues.

See some of our publications for more information about the principles:

Spectroscopic measurement of cartilage thickness in arthroscopy: Ex vivo validation in human knee condyles. Johansson A, Kuiper J-H, Sundqvist T, Persson F, Speier C, D’Alfonso D, Richardson JB, Öberg Å. Arthroscopy, 28, 1513-1523, 2012.

A spectroscopic approach to imaging and quantification of cartilage lesions in human knee joints. Johansson A, Sundqvist T, Kuiper J-H, Öberg PÅ. Phys. Med. Biol., 56, 1865-1878, 2011.

Assessment of cartilage thickness utilising reflectance spectroscopy. Öberg PÅ, Sundqvist T, Johansson A. Med. Biol. Eng. Comput., 42, 3-8, 2004.
Diffuse reflectance spectroscopy of the human tympanic membrane in otitis media. Sundberg M, Peebo M, Öberg PÅ, Lundquist PG, Strömberg T. Physiol. Meas. 25, 1473-1483, 2004.

Assessment of cartilage thickness utilising reflectance spectroscopy. Johansson A, Öberg PÅ, Sundqvist T, Sundberg M. 12th Nordic Baltic Conf. on Biomedical Eng., Iceland, 2002.

Characterisation of the cartilage/bone interface utilising reflectance spectroscopy. Öberg PÅ, Sundqvist T, Johansson A, Sundberg M. Proc. 23rd An. Int. Conf. IEEE EMBS, Istanbul, 2001.